DLA-DRB1, DQA1, and DQB1 Alleles and Haplotypes in North American Gray Wolves

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DLA-DRB1, DQA1, and DQB1 alleles and haplotypes in North American Gray Wolves.

The canine major histocompatibility complex contains highly polymorphic genes, many of which are critical in regulating immune response. Since domestic dogs evolved from Gray Wolves (Canis lupus), common DLA class II alleles should exist. Sequencing was used to characterize 175 Gray Wolves for DLA class II alleles, and data from 1856 dogs, covering 85 different breeds of mostly European origin,...

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Association of HLA-DRB1, DQA1 and DQB1 Alleles and Haplotypes with Common Variable Immunodeficiency in Iranian Patients

Common Variable Immunodeficiency (CVID) is an antibody deficiency syndrome that often co-occurs in families with selective IgA deficiency (IgAD). This study was designed to investigate the frequency of DR and DQ loci of HLA class II region in common variable immunodeficiency (CVID) patients. Fifteen Iranian patients with CVID or IgAD (mean age 14.6±5.4, range 4-25 years; 9 male and 6 female) an...

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association of hla-drb1, dqa1 and dqb1 alleles and haplotypes with common variable immunodeficiency in iranian patients

common variable immunodeficiency (cvid) is an antibody deficiency syndrome that often co-occurs in families with selective iga deficiency (igad). this study was designed to investigate the frequency of dr and dq loci of hla class ii region in common variable immunodeficiency (cvid) patients. fifteen iranian patients with cvid or igad (mean age 14.6±5.4, range 4-25 years; 9 male and 6 female) an...

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HLA-DRB1, DQA1 and DQB1 alleles and haplotypes frequencies in Iranian healthy adult responders and non-responders to recombinant hepatitis B vaccine.

BACKGROUND Different studies have demonstrated that a small proportion of healthy individuals receiving the hepatitis B (HB) vaccine do not produce protective levels of anti-HB antibody, a phenomenon which could be linked to certain human leukocyte antigen (HLA) class-II alleles or haplotypes. OBJECTIVES The present study was undertaken to determine the frequency of HLA class-II alleles in Ir...

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HLA class I (A, B, C) and class II (DRB1, DQA1, DQB1, DPB1) alleles and haplotypes in the Han from southern China.

In this study, polymerase chain reaction-sequence-specific oligonucleotide prode (SSOP) typing results for the human leukocyte antigen (HLA) class I (A, B, and C) and class II (DRB1, DQA1, DQB1, and DPB1) loci in 264 individuals of the Han ethnic group from the Canton region of southern China are presented. The data are examined at the allele, genotype, and haplotype level. Common alleles at ea...

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ژورنال

عنوان ژورنال: Journal of Heredity

سال: 2007

ISSN: 1465-7333,0022-1503

DOI: 10.1093/jhered/esm051